Single-Nucleotide Polymorphism Array-Based Karyotyping of Acute Promyelocytic Leukemia
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چکیده
منابع مشابه
Single-Nucleotide Polymorphism Array-Based Karyotyping of Acute Promyelocytic Leukemia
Acute promyelocytic leukemia (APL) is characterized by the t(15;17)(q22;q21), but additional chromosomal abnormalities (ACA) and other rearrangements can contribute in the development of the whole leukemic phenotype. We hypothesized that some ACA not detected by conventional techniques may be informative of the onset of APL. We performed the high-resolution SNP array (SNP-A) 6.0 (Affymetrix) in...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0100245